4,4,5,5,5-Pentafluoro-1-pentanethiol is a useful building block and intermediate employed in the preparation and fluorination of fulvestrant 11β isomers which shows antiproliferative activity on MCF-7 cells for breast cancer treatment. It also used as an important chain of anti-breast cancer agent.
Laboratory scale preparation of 4,4,5,5,5-pentafluoropentan-1-thiol: An important chain of anti-breast cancer agents. 
Antiestrogenic activities of 3,8-dihydroxy-6,11-dihydrobenzo[a]carbazoles with sulfur-containing side chains. 
Effect of Fluorination on the Pharmacological Profile of 11β Isomers of Fulvestrant in Breast Carcinoma Cells. 
An alternative synthesis of the breast cancer drug fulvestrant (Faslodex®): catalyst control over C–C bond formation. 
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