2,2,2-Trifluoroethylamine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-Amino-1,1,1-trifluoroethane
Trifluoroethylated Building Blocks, API&Intermediates
KUMI3F252
753-90-2
MFCD00008132
9773
1733204
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
2,2,2-Trifluoroethylamine
CF3CH2NH2
99.06
≥99%
Colorless to Slightly pale yellow Liquid
36-38°C
5g,25g,50g,100g,250g,500g and 1kg
Store locked-up, in a cool, well-ventilated place
2,2,2-Trifluoroethylamine is a trifluoroethoxylated building block that commonly used in organic synthesis. A typical example is employed in the preparation of ABT-494 as a potent and selective JAK inhibitors in the treatment of Rheumatoid Arthritis.
A Phase IIb Study of ABT-494, a Selective JAK-1 Inhibitor, in Patients With Rheumatoid Arthritis and an Inadequate Response to Anti-Tumor Necrosis Factor Therapy. [1]
Reference:
[1] J.M.Kremer, et al, Arthritis Rheumatol., 2016, 68(12), pp 2867-2877.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P271,P280,P305+P351+P338
2931900090
NONH for all modes of transport
 
1. Product Specification
2. Safety Data Sheet
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