2,2,2-Trifluoroethyl trifluoromethanesulfonate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Trifluoromethanesulfonic acid 2,2,2-trifluoroethyl ester, CF3CH2OTf
Trifluoroethylating Reagents
KUMI6F103
6226-25-1
MFCD00671579
80366
2051235
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
2,2,2-Trifluoroethyl trifluoromethanesulfonate
C3H2F6O3S
232.10
≥99%
Colorless to Light yellow Liquid
90-91°C
100g,250g,500g,1kg, 25kg and 50kg
Store locked-up, in a cool, well-ventilated place
2,2,2-Trifluoroethyl trifluoromethanesulfonate (also named as Trifluoromethanesulfonic acid 2,2,2-trifluoroethyl ester, Trifluoroethanol triflate) is a powerful trifluoroethylating agent typically used for synthesis of fluorinated amino acids. It is also used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.
A facile synthesis of 1-H-2,2-difluorovinylphosphorus compounds from 2,2,2-trifluoroethyl trifluoromethanesulfonate and substitutions of their vinylic fluorines. [1]
A general strategy for the synthesis of cyclic N-aryl hydroxamic acids via partial nitro group reduction. [2]
References:
[1] J.Ichikawa, et al, J. F. Chem., 1999, 97(1-2), pp 109-114.
[2] L.A.McAllister, et al, J. Org. Chem., 2011, 76(9), pp 3484-3497.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H301,H314,H330
P260,P280,P284,P301+P310,P305+P351+P338,P310
2905599890
UN 3265 8/PG II
 
1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.